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Backgrounds/Aims: Gastric variceal bleeding is difficult to treat endoscopically because the hemodynarnics of the gastric varix are different from that of the esophageal varix. Transjugular intrahepatic uortosystemic shunt (TIPS), which lias been used widely, does not always result in the regression of gastric varix and it may aggravate the hepatic encephalopathy, Balloon occluded retrograde transverious obliteration (BRTO) was introduced as a new procedure for gastric variceal bleeding with, minimal invasiveness. The purpose of this study was to evaluate the therapeutic effects and complications on follow-up of BRTO as a new treatment option for gastric variceal bleeding. Methods: Patients with gastric variceal bleeding, wl1o were treated with BRTO form September, 2001 to April, 2003, were included- in the study. After -the definite confirmation of the shunts with abdominal CT, the sclerosing agent, 5% ethanolamine oleate, was injected into the gastric varix during occlusion through gastrorenal shunts. The procedurre was deemed a technical success when the clotting of the sclerosing agent was observed without leakage, and a clinical success when bleeding stopped and the varix decreased in size or was eradicated during the follow-up period (6-23 months, mean: 17.7). Results: Technical success was achieved in 12 of 13 patients (92%) with gastric variceal bleeding. There were no significant side effects. In the one case of failure, the bleeding was controlled with TIPS. Eleven of the 12 patients who had technical success were shown to be clinically successful. The follow-up endoscopic exam showed some aggravation of pre-existing esophageal varices in four patients and a new development of esophageal varices in two patients. Endoscopic variceal ligation was done on one patient in whom esophageal variceal bleeding was present during the follow-up period Conclusions: BRTO was proven to be a-feasible, safe and less invasive procedure than TIPS and found to be an effective treatment of a gastric variceal bleeding. Considering the possible aggravation of pre-existing esophageal varices or the new development of esophageal varices, regular endoscopic examinations might be needed during the follow-up period (Korean J Hepatol 2003; 9315-323)
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